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The 33-year-old fired a two-under-par final round of 70 to finish at 20 under par, two shots ahead of Northern Ireland's Michael Hoey and the South African Danie van Tonder.
Fisher pulled on his golf clothing on Sunday morning five shot clear of the field but soon came under pressure from Hoey, who had closed the gap to just two shots at the start of the back nine.
Hoey moved within a shot of the lead after another birdie at 11, before carding a double-bogey six on the par-four 12th to hand Fisher back a three-stroke advantage.
An eagle on the par-five 15th handed the Englishman a four-shot lead with three holes to play, which allowed him the cushion to drop a shot on the 18th as he cruised home at Copperleaf Golf & Country Estate.
"It's been pretty good to me this week (the 15th hole)," Fisher told Europeantour.com. "There have been a couple of eagles, but that was a big putt there.
"I know I was only a couple ahead. To hit a nice shot there and have a good look at three and to see it drop - I think I went four shots clear with only three to play I knew I could coast in.
"There was a little wobble on a few of those holes and I managed to make a couple of good par saves on 16 and 17.
"It would have been nice to shoot 69 but unfortunately I missed one on the last. I'm not going to complain."
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